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KMID : 0388420020120010085
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Konkuk Journal of Medical Sciences
2002 Volume.12 No. 1 p.85 ~ p.92
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Diagnostic Value of Transbronchial Lung Biopsy in Histologic Diagnosis of Solitary Pulmonary Nodule
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Kim Chi-Hun
Wang Joon-Ho
Kim Hyeong-Su
Kim Chong-Ju
Yeon Kyu-Min
Lee Won-Yeon
Yong Suk-Joong
Shin Kye-Chul
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Abstract
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Transbronchial lung biopsy(TBLB) is a relatively simple and convenient diagnostic tool in solitary pulmonary nodule(SPN) on chest radiograph, which is cannot be diagnosed through routine tests. To investigate the diagnostic value and diagnostic rate of TBLB according to the variable factor, we analyzed 69 patients with radiologically SPN lesion on chest radiograph which was confirmed histologically. A histologic diagnosis of TBLB was made in 47 of 69 patients (68. 1 %), in which 26 of 37(70.3%) with malignancy and 21 of 32(65.6%) with benign lesion. There were no significant differences in diagnostic yield according to age, sex and location of the lesion. The diagnostic rate tended to increase with the more than 5 pieces to acquired by TBLB. When the size of SPN was less than 3 cm, it cannot be diagnosed.
In conclusion, TBLB is a diagnostic procedure with good yield and safety, but percutaneous needle aspiration, transbronchial needle aspiration, and bronchial washing fluid cytology may be a complementary procedure to overcome the limitation of TBLB and get higher diagnostic yield for SPN.
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KEYWORD
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SPN, TBLB
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